Instituto de Física Teórica UAM/CSIC (Webpage 2008-2015)

After a very brief introduction on the most recent results on Dark Matter (DM) in Astrophysics and Cosmology, I will review the motivations to go beyond an "accelerator-only" approach, and highlight the benefits of multidisciplinarity in the quest for DM. Given the large astrophysical uncertainties inevitably associated to direct and indirect DM searches, I will tackle the question of whether it is possible to obtain trustworthy information, and possibly to *discover*, Dark Matter particles, by means of astrophysical measurements. Finally, I will discuss a recently proposed astrophysical scenario where the formation of Intermediate Mass Black Holes leads to large DM overdensities dubbed "spikes", and discuss its consequences for Indirect DM searches.